2-(4-氯苯基)-噻唑-4-羧酸乙酯合成路线 (共 7 条)
反应条件
oxygen; copper diacetate in N,N-dimethyl-formamide T=120°C; P=760.051 Torr; 12 h; Molecular sieve;
参考文献
Wang, Yiyun; Li, Ziyuan; Huang, Yue; Tang, Changhua; Wu, Xiaoming; Xu, Jinyi; Yao, Hequan
Tetrahedron, 2011 , vol. 67, # 38 p. 7406 - 7411
反应条件
potassium carbonate in N,N-dimethyl-formamide T=80°C; 2 h; Molecular sieve;
参考文献
Huang, Yue; Gan, Haifeng; Li, Shang; Xu, Jinyi; Wu, Xiaoming; Yao, Hequan
Tetrahedron Letters, 2010 , vol. 51, # 13 p. 1751 - 1753
反应条件
boron trifluoride diethyl etherate 3 h; Heating;
参考文献
Kim, Hong-Seok; Kwon, Il-Cheon; Kim, Oh-Hwoan
Journal of Heterocyclic Chemistry, 1995 , vol. 32, # 3 p. 937 - 940
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 20 p. 3491 - 3495
反应条件
1: sodium hydride; 18-crown-6 ether / toluene / 3 h / 20 - 60 °C / |Cooling with ice 2: Lawesson's reagent / 1,4-dioxane / 12 h / |Reflux View Scheme
参考文献
Tetrahedron Letters, , vol. 55, # 16 p. 2671 - 2674
反应条件
in ethanol 8 h; Reflux;
参考文献
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, , vol. 67, # 7 p. 747 - 758
反应条件
potassium hydroxide T=50°C;
参考文献
Larsen, Scott D.; Stachew, Carl F.; Clare, Paula M.; Cubbage, Jerry W.; Leach, Karen L.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 20 p. 3491 - 3495