N,N'-二甲基-1,2-环己二胺合成路线 (共 21 条)
反应条件
<b>Multi-step reaction with 4 steps<br /> </b>1.1: water / 5 h / 80 °C / |Cooling with ice; |Sealed tube<br />2.1: triphenylphosphine; diethylazodicarboxylate / dichloromethane / 6 h / 20 °C / |Cooling with ice<br />3.1: ammonium chloride / water / 5 h / 110 °C / |Sealed tube<br />4.1: L-(+)-tartaric acid / ethanol / 1 h / 20 °C / |Reflux; |Resolution of racemate<br />4.2: 20 °C / pH 9-10 / |Reflux; |Resolution of racemate<br /> <br />
参考文献
Shen, Yan-Hong; Ye, Qing; Hou, Shao-Gang; Wang, Qun Journal of Chemical Research, 2013 , vol. 37, # 4 p. 191 - 192