2,6-二氯-4-硝基苯酚合成路线 （共 42 条）
反应条件
1: 1.) NaH / 1.) DMF, 40 min, 2.) DMF, from 5 to 70 deg C, 40 min
2: 0.17 h / 175 - 180 °C
View Scheme
参考文献
Miller; Mylari; Howes Jr.; Figdor; Lynch; Koch
Journal of Medicinal Chemistry, 1980 , vol. 23, # 10 p. 1083 - 1087
反应条件
potassium carbonate; Raney-Ni in N,N-dimethyl-formamide
T=60°C; 6 h; Inert atmosphere;
参考文献
FOREST LABORATORIES HOLDINGS LIMITED; SARMA, Pakala Kumara, Savithru; ACHARYA, Vinod, Parameshwaran; KASIBHATLA, Srinivas, Rao; TIWARI, Atul; REDDY, Vantaddu, Nagarjuna; BISCHOFF, Alexander
Patent: WO2010/127208 A1, 2010 ;
Location in patent: Page/Page column 57 ;
