1-氯-3,5-二硝基苯合成路线 （共 15 条）
反应条件
(NH4)2S in ethanol; water 1 h; Heating / reflux;
参考文献
Boehringer Ingelheim Pharmaceuticals, Inc.
Patent: US6353013 B1, 2002 ;
Location in patent: Page column 28 ;
参考文献
Cohen; Mc Candlish
Journal of the Chemical Society, 1905 , vol. 87, p. 1265
反应条件
methanol; sodium hydroxide; nickel Hydrogenation;
参考文献
Boyle-Midway Inc.
Patent: US2464044 , 1946 ;
反应条件
hydrogenchloride; sulfuric acid; nitric acid
T=130°C; 0.666667 h; Product distribution;
参考文献
Melhuish, Martin W.; Moodie, Roy B.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1989 , p. 667 - 674
反应条件
1: aq. (NH4)2S
2: (i) Py, (ii) /BRN= 635994/, aq. NaOH
View Scheme
参考文献
White,W.N.; Klink,J.R.
Journal of Organic Chemistry, 1977 , vol. 42, # 1 p. 166 - 169
