(R)-(+)-1-(4-溴苯基)异氰酸乙酯合成路线 (共 2 条)
反应条件
sodium hydrogencarbonate in dichloromethane; water
T=0°C; 0.25 h; Inert atmosphere;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; FANDRICK, Keith R.; GAO, Ju; LI, Wenjie; LU, Bruce; ZHANG, Yongda
Patent: WO2010/10150 A1, 2010 ;
Location in patent: Page/Page column 46 ;
WO 2010/010150 A1
反应条件
in hydrogenchloride; ethyl acetate; toluene
参考文献
Behrens, Carsten; Lau, Jesper; Madsen, Peter
Patent: US2003/203946 A1, 2003 ;
US 20030203946 A1