3,4-二(四氢吡喃-2-氧基)苯甲醛合成路线 （共 5 条）
反应条件
Ba(OH)2*8H2O in methanol T=40°C; Condensation; 12 h;
参考文献
Lin, Chun-Nan; Lee, Tai-Hua; Hsu, Mei-Feng; Wang, Jih-Pyang; Ko, Feng-Nien; Teng, Che-Ming
Journal of Pharmacy and Pharmacology, 1997 , vol. 49, # 5 p. 530 - 536
反应条件
1: barium hydroxide octahydrate / methanol / 19 h / 50 °C 2: p-toluenesulfonic acid / methanol / 15 h / Ambient temperature View Scheme
参考文献
Sogawa; Nihro; Ueda; Izumi; Miki; Matsumoto; Satoh
Journal of Medicinal Chemistry, 1993 , vol. 36, # 24 p. 3904 - 3909
反应条件
1: 1.) NaH, DMSO / 1.) 70-80 deg C, 15 min, then room t., 20 min, 2.) DMSO, room t., 1.5 h 2: 58 percent / pTs-OH / methanol / 2 h / 0 °C View Scheme
参考文献
Sugiura; Naito; Yamaura; Fukaya; Yokoyama
Chemical and Pharmaceutical Bulletin, 1989 , vol. 37, # 4 p. 1039 - 1043
反应条件
1: partially dehydrated barium hydroxide octahydrate / ethanol / 2 h / Heating 2: p-toluenesulfonic acid / methanol / 4 h / 20 °C View Scheme
参考文献
Sogawa; Nihro; Ueda; Izumi; Miki; Matsumoto; Satoh
Journal of Medicinal Chemistry, 1993 , vol. 36, # 24 p. 3904 - 3909
反应条件
4-Methyl-benzene sulfinic acid in tetrahydrofuran; dichloromethane
2 h; Ambient temperature;
参考文献
Li, Shu Wen; Elliot, William H.; Burke, William J.
Bioorganic Chemistry, 1994 , vol. 22, # 4 p. 337 - 342
