4'-氯-5-甲基磺酰基氧基-3-联苯乙酸甲酯合成路线 （共 9 条）
反应条件
1: (i) NaOMe, MeOH, (ii) aq. NaOH, (iii) aq. HCl
2: POCl3, Na2CO3 / toluene
3: Na / toluene
4: Br2 / benzene
5: aq. NaOH / methanol
6: aq. HBr, AcOH
7: H2SO4 / benzene
8: Py
View Scheme
参考文献
Tamura,Y. et al.
Journal of Medicinal Chemistry, 1977 , vol. 20, p. 709 - 714
反应条件
1: POCl3, Na2CO3 / toluene
2: Na / toluene
3: Br2 / benzene
4: aq. NaOH / methanol
5: aq. HBr, AcOH
6: H2SO4 / benzene
7: Py
View Scheme
参考文献
Tamura,Y. et al.
Journal of Medicinal Chemistry, 1977 , vol. 20, p. 709 - 714
反应条件
1: H2SO4 / benzene
2: Py
View Scheme
参考文献
Tamura,Y. et al.
Journal of Medicinal Chemistry, 1977 , vol. 20, p. 709 - 714
反应条件
1: aq. NaOH / methanol
2: aq. HBr, AcOH
3: H2SO4 / benzene
4: Py
View Scheme
参考文献
Tamura,Y. et al.
Journal of Medicinal Chemistry, 1977 , vol. 20, p. 709 - 714
反应条件
1: aq. HBr, AcOH
2: H2SO4 / benzene
3: Py
View Scheme
参考文献
Tamura,Y. et al.
Journal of Medicinal Chemistry, 1977 , vol. 20, p. 709 - 714
反应条件
1: Br2 / benzene
2: aq. NaOH / methanol
3: aq. HBr, AcOH
4: H2SO4 / benzene
5: Py
View Scheme
参考文献
Tamura,Y. et al.
Journal of Medicinal Chemistry, 1977 , vol. 20, p. 709 - 714
反应条件
1: Na / toluene
2: Br2 / benzene
3: aq. NaOH / methanol
4: aq. HBr, AcOH
5: H2SO4 / benzene
6: Py
View Scheme
参考文献
Tamura,Y. et al.
Journal of Medicinal Chemistry, 1977 , vol. 20, p. 709 - 714
反应条件
1: aq. NaOH
2: (i) NaOMe, MeOH, (ii) aq. NaOH, (iii) aq. HCl
3: POCl3, Na2CO3 / toluene
4: Na / toluene
5: Br2 / benzene
6: aq. NaOH / methanol
7: aq. HBr, AcOH
8: H2SO4 / benzene
9: Py
View Scheme
参考文献
Tamura,Y. et al.
Journal of Medicinal Chemistry, 1977 , vol. 20, p. 709 - 714
参考文献
Tamura,Y. et al.
Journal of Medicinal Chemistry, 1977 , vol. 20, p. 709 - 714
