2-溴甲基-6-硝基苯甲酸甲酯合成路线 （共 8 条）
反应条件
N-bromosuccinmide; dibenzoyl peroxide in tetrachloromethane T=80°C; 16 h;
参考文献
Deshpande, Girish Nilkanth; Weipert, Paul David; Ensley, Michael W.
Patent: US2011/251395 A1, 2011 ;
Location in patent: Page/Page column 15 ;
反应条件
1: DIPEA / acetone 2: NBS; (PhCO)2O2 / CCl4 / Irradiation View Scheme
参考文献
Synthesis, , # 7 p. 981 - 983
反应条件
in tetrachloromethane; ethyl acetate
反应条件
4-methylmorpholine N-oxide in acetonitrile T=20°C; 20 h;
参考文献
Vu, Chi B.
Patent: US2013/190309 A1, 2013 ;
Location in patent: Paragraph 0393; 0394 ;
反应条件
1.1: ethanol; tetrahydrofuran / 2 h 2.1: hydrogen / 5 palladium on charcoal / dichloromethane; ethanol / 2068.65 Torr 3.1: N-bromosuccinmide / dichloromethane / 1 h / -10 - -8 °C 3.2: 0.33 h View Scheme
参考文献
WO2012/74951 A1, ;
WO 2012/074951 A1
反应条件
ammonia in methanol; N,N-dimethyl-formamide
T=25°C; 20 h;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
Patent: WO2006/21544 A1, 2006 ;
Location in patent: Page/Page column 26 ;
WO 2006/021544 A1
反应条件
1: 75 percent / pyridine / ethanol / 48 h / Heating
2: H2 / Pd/C / ethyl acetate / 3 h
View Scheme
参考文献
Suizu, Mamiko; Muroya, Yohei; Kakuta, Hiroki; Kagechika, Hiroyuki; Tanatani, Aya; Nagasawa, Kazuo; Hashimoto, Yuichi
Chemical and Pharmaceutical Bulletin, 2003 , vol. 51, # 9 p. 1098 - 1102
反应条件
sodium methylate in methanol; water
参考文献
Bristol-Myers Company
Patent: US3988340 A1, 1976 ;
