1,2-二甲基-4-(1-苯乙基)苯合成路线 （共 19 条）
反应条件
1: With oxygen; 2-hydroxy-1,3-isoindolinedione; 2,2'-azo-bisisobutyronitrile in acetonitrile T=75°C; P=760.051 Torr; 6 h; 2: With sulfuric acid in water; acetonitrile T=0°C; 0.5 h;
参考文献
EP1967505 A1, ;
Page/Page column 14 ;
反应条件
1: With oxygen; 2-hydroxy-1,3-isoindolinedione; 2,2'-azo-bisisobutyronitrile in acetonitrile T=75°C; P=760.051 Torr; 6 h; 2: With sulfuric acid in water; acetonitrile T=0°C; 0.5 h;
参考文献
EP1967505 A1, ;
Page/Page column 14 ;
反应条件
[Ir2(COD)2(SnCl3)2(Cl)2)(μ-Cl)2] in 1,2-dichloro-ethane
T=80°C; 12 h;
参考文献
Podder, Susmita; Choudhury, Joyanta; Roy, Sujit
Journal of Organic Chemistry, 2007 , vol. 72, # 8 p. 3129 - 3132
反应条件
amberlyst-15 in nitromethane
T=90°C; Microwave irradiation;
参考文献
Rueping, Magnus; Bootwicha, Teerawut; Sugiono, Erli
Advanced Synthesis and Catalysis, 2010 , vol. 352, # 17 p. 2961 - 2965
反应条件
anhydrous iron chloride in 1,2-dichloro-ethane
T=20°C; Friedel-Crafts Alkylation; 1 h; Inert atmosphere; Reagent/catalystTime; regioselective reaction;
参考文献
Sawama, Yoshinari; Shishido, Yuko; Kawajiri, Takahiro; Goto, Ryota; Monguchi, Yasunari; Sajiki, Hironao
Chemistry - A European Journal, 2014 , vol. 20, # 2 p. 510 - 516
反应条件
anhydrous iron chloride in 1,2-dichloro-ethane
T=20°C; Friedel-Crafts Alkylation; 1.5 h; Inert atmosphere; regioselective reaction;
参考文献
Sawama, Yoshinari; Shishido, Yuko; Kawajiri, Takahiro; Goto, Ryota; Monguchi, Yasunari; Sajiki, Hironao
Chemistry - A European Journal, 2014 , vol. 20, # 2 p. 510 - 516
反应条件
anhydrous iron chloride in 1,2-dichloro-ethane
T=20°C; Friedel-Crafts Alkylation; 2.5 h; Inert atmosphere; regioselective reaction;
参考文献
Sawama, Yoshinari; Shishido, Yuko; Kawajiri, Takahiro; Goto, Ryota; Monguchi, Yasunari; Sajiki, Hironao
Chemistry - A European Journal, 2014 , vol. 20, # 2 p. 510 - 516
反应条件
anhydrous iron chloride; chloro-trimethyl-silane in 1,2-dichloro-ethane
T=20°C; Friedel-Crafts Alkylation; 0.166667 h; Inert atmosphere;
参考文献
Sawama, Yoshinari; Shishido, Yuko; Kawajiri, Takahiro; Goto, Ryota; Monguchi, Yasunari; Sajiki, Hironao
Chemistry - A European Journal, 2014 , vol. 20, # 2 p. 510 - 516
反应条件
iron(III) chloride
T=80°C; 4 h;
参考文献
Kischel, Jette; Jovel, Irina; Mertins, Kristin; Zapf, Alexander; Beller, Matthias
Organic Letters, 2006 , vol. 8, # 1 p. 19 - 22
反应条件
iron(III) chloride
T=80°C; Friedel-Crafts alkylation; 24 h;
参考文献
Iovel, Irina; Mertins, Kristin; Kischel, Jette; Zapf, Alexander; Beller, Matthias
Angewandte Chemie - International Edition, 2005 , vol. 44, # 25 p. 3913 - 3917
