1,2-二甲基-4-(1-苯乙基)苯合成路线 （共 19 条）
反应条件
anhydrous iron chloride; bis-trimethylsilyl ether in 1,2-dichloro-ethane
T=20°C; Friedel-Crafts Alkylation; 0.5 h; Inert atmosphere;
参考文献
Sawama, Yoshinari; Shishido, Yuko; Kawajiri, Takahiro; Goto, Ryota; Monguchi, Yasunari; Sajiki, Hironao
Chemistry - A European Journal, 2014 , vol. 20, # 2 p. 510 - 516
反应条件
dihydrogen hexachloroplatinate
T=80°C; Friedel-Crafts alkylation; 1 h;
参考文献
Iovel, Irina; Mertins, Kristin; Kischel, Jette; Zapf, Alexander; Beller, Matthias
Angewandte Chemie - International Edition, 2005 , vol. 44, # 25 p. 3913 - 3917
反应条件
1: o-xylene; anhydrous iron chloride / 1,2-dichloro-ethane / 0.12 h / 20 °C / |Inert atmosphere
2: anhydrous iron chloride; chloro-trimethyl-silane / 1,2-dichloro-ethane / 0.17 h / 20 °C / |Inert atmosphere
View Scheme
参考文献
Sawama, Yoshinari; Shishido, Yuko; Kawajiri, Takahiro; Goto, Ryota; Monguchi, Yasunari; Sajiki, Hironao
Chemistry - A European Journal, 2014 , vol. 20, # 2 p. 510 - 516
反应条件
AlCl3, aluminium chloride in 1,2-dichloro-ethane
T=20°C; 3 h; Inert atmosphere;
参考文献
Sawama, Yoshinari; Shishido, Yuko; Kawajiri, Takahiro; Goto, Ryota; Monguchi, Yasunari; Sajiki, Hironao
Chemistry - A European Journal, 2014 , vol. 20, # 2 p. 510 - 516
反应条件
tin(IV) chloride
1 h; Ambient temperature;
参考文献
Ono, Noboru; Yanai, Tetsuya; Kamimura, Akio; Kaji, Aritsune
Journal of the Chemical Society, Chemical Communications, 1986 , # 16 p. 1285 - 1287
反应条件
bismuth trifluoromethanesulphonate
T=100°C; Friedel-Crafts-type benzylation; 1 h;
参考文献
Rueping, Magnus; Nachtsheim, Boris J.; Ieawsuwan, Winai
Advanced Synthesis and Catalysis, 2006 , vol. 348, # 9 p. 1033 - 1037
反应条件
1: pyridine / dichloromethane / 0 - 20 °C
2: [1-butyl-3-methylimidazolium][FeCl4] / 12 h / 80 °C
View Scheme
参考文献
Gao, Jian; Wang, Jin-Quan; Song, Qing-Wen; He, Liang-Nian
Green Chemistry, 2011 , vol. 13, # 5 p. 1182 - 1186
反应条件
iodine
T=130°C; Friedel-Crafts Reaction; 2 h;
参考文献
Chu, Cheng-Ming; Huang, Wan-Ju; Liu, Ju-Tsung; Yao, Ching-Fa
Tetrahedron Letters, 2007 , vol. 48, # 39 p. 6881 - 6885
反应条件
toluene-4-sulfonic acid; hydroquinone
T=110°C; 11.5 h; Yield given. Yields of byproduct given;
参考文献
Zaitsev, B. A.; Kiseleva, R. F.; Denisov, V. M.; Kol'tsov, A. I.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1990 , vol. 39, # 11 p. 2323 - 2330
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1990 , # 11 p. 2566 - 2574
