(9ci)-1H-咪唑-1-羧酸甲酯合成路线 （共 41 条）
反应条件
1: C6H15N*C51H78F3N8O28P; 1,1'-carbonyldiimidazole in tetrahydrofuran; N,N-dimethyl-formamide
T=20°C; 2 h;
2: methanol in tetrahydrofuran; N,N-dimethyl-formamide
T=20°C; 0.5 h;
参考文献
Mitachi, Katsuhiko; Mohan, Priya; Siricilla, Shajila; Kurosu, Michio
Chemistry - A European Journal, 2014 , vol. 20, # 16 p. 4554 - 4558
反应条件
2 h; Inert atmosphereHeating;
参考文献
Heller, Stephen T.; Sarpong, Richmond
Tetrahedron, 2011 , vol. 67, # 46 p. 8851 - 8859
反应条件
in acetonitrile
T=80°C; 24 h; Inert atmosphereSealed vial;
参考文献
Heller, Stephen T.; Sarpong, Richmond
Tetrahedron, 2011 , vol. 67, # 46 p. 8851 - 8859
反应条件
in acetonitrile
T=80°C; 24 h; Inert atmosphere; regioselective reaction;
参考文献
Heller, Stephen T.; Sarpong, Richmond
Tetrahedron, 2011 , vol. 67, # 46 p. 8851 - 8859
反应条件
sodium hydride
1.) DMF, r.t., 15 min; 2.) DMF, 30 min; Yield given. Multistep reaction;
参考文献
Hengartner, Urs; Muller, Jean-Claude; Ramuz, Henri
Helvetica Chimica Acta, 1983 , vol. 66, # 2 p. 669 - 672
反应条件
sodium hydride
1.) hexane, DMF, r.t., 30 min; 2.) DMF, 20-25 deg C, 1 h; Yield given. Multistep reaction;
参考文献
Hoffmann-La Roche Inc.
Patent: US4360521 A1, 1982 ;
反应条件
in acetonitrile
T=80°C; 24 h; Inert atmosphere; chemoselective reaction;
参考文献
Heller, Stephen T.; Sarpong, Richmond
Organic Letters, 2010 , vol. 12, # 20 p. 4572 - 4575
反应条件
T=750°C; P=0.001 Torr; Title compound not separated from byproducts;
参考文献
Maquestiau, A.; Tommasetti, A.; Pedregal-Freire, C.; Elguero, J.; Flammang, R.; et al.
Journal of Organic Chemistry, 1986 , vol. 51, # 3 p. 306 - 309
反应条件
T=750°C; P=0.001 Torr; Title compound not separated from byproducts;
参考文献
Maquestiau, A.; Tommasetti, A.; Pedregal-Freire, C.; Elguero, J.; Flammang, R.; et al.
Journal of Organic Chemistry, 1986 , vol. 51, # 3 p. 306 - 309
反应条件
in dimethyl sulfoxide
36 h; Ambient temperature; Yield given;
参考文献
Crumbie, Robyn L.; Nimitz, Jonathan S.; Mosher, Harry S.
Journal of Organic Chemistry, 1982 , vol. 47, # 21 p. 4040 - 4045
