1-苄基哌啶-3,3-二醇氢溴酸合成路线 （共 4 条）
反应条件
triethylamine in dichloromethane 3 h;
参考文献
Schering Corporation
Patent: US2008/4286 A1, 2008 ;
Location in patent: Page/Page column 15; 16 ;
US 20080004286 A1
反应条件
hydrogen; palladium on activated charcoal in ethanol; water P=2205.2 Torr;
参考文献
Brehm, Lotte; Krogsgaard-Larsen, Povl; Schaumburg, Kjeld; Johansen, Joergen S.; Falch, Erik; Curtis, David R.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 2 p. 224 - 229
反应条件
1: H2 / 10percent Pd/C / ethanol; H2O / 2205.2 Torr 2: triethylamine / tetrahydrofuran / 2 h / 0 °C View Scheme
参考文献
Brehm, Lotte; Krogsgaard-Larsen, Povl; Schaumburg, Kjeld; Johansen, Joergen S.; Falch, Erik; Curtis, David R.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 2 p. 224 - 229
反应条件
water; hydrogen bromide
3 h; Heating / reflux;
参考文献
Schering Corporation
Patent: US2008/4286 A1, 2008 ;
Location in patent: Page/Page column 15 ;
US 20080004286 A1
