1.1: O-(2,4-dinitro-phenyl)-hydroxylamine / acetonitrile / 18 h / 40 °C 1.2: 18 h / 20 °C 2.1: sulfuric acid; water / 18 h / Reflux 2.2: pH 7 View Scheme
Hamblett, Christopher L.; Sloman, David L.; Kliman, Laura T.; Adams, Bruce; Ball, Richard G.; Stanton, Matthew G.
Tetrahedron Letters, 2007 , vol. 48, # 12 p. 2079 - 2082
1: 4-methoxy pyridine With lithium diisopropyl amide in tetrahydrofuran; n-heptane; ethylbenzene T=-25°C; 0.5 h; 2: triisopropylsilyl chloride in tetrahydrofuran; n-heptane; ethylbenzene T=-25 - 20°C; 16.25 h;
参考文献
Brotherton-Pleiss, Christine E.; Caroon, Joan Marie; Lopez-Tapia, Francisco Javier
Patent: US2010/160388 A1, 2010 ;
Location in patent: Page/Page column 50-51 ;
US 20100160388 A1