1: C10H8BrF3 With copper(I) thiophene-2-carboxylate; (S)-(-)-N-(2,2-dimethylpropionyl)-2-lt;(diphenylphosphino)methylgt;pyrrolidine in dichloromethane Inert atmosphere; 2: phenyl-magnesium bromide in diethyl ether; dichloromethane T=-78°C; Inert atmosphere; optical yield given as percent eeenantioselective reaction;

1: C10H8BrF3 With [(4S,5S)-1,3-bis(bis(2-methylphenyl)methyl)-4,5-diphenylimidazolidin-2-ylidene]copper(I) chloride in dichloromethane T=-78°C; Inert atmosphere; 2: phenyl-magnesium bromide in diethyl ether; dichloromethane T=-78°C; 0.5 h; Inert atmosphere; optical yield given as percent eeregioselective reaction;

FeCl3·6H2O; benzyl alcohol in toluene T=80°C; 2 h; chemoselective reaction;

C22H46N4; palladium diacetate; Ca(OH)2 in N,N-dimethyl acetamide; water T=20 - 50°C; 6 h; Inert atmosphere; Overall yield = 63 percent;

C22H46N4; palladium diacetate; Ca(OH)2 in N,N-dimethyl acetamide; water T=20 - 50°C; 6 h; Inert atmosphere; Overall yield = 80 percent;

1: With di-μ-chloro-bis(η4-1,5-cyclooctadiene)diiridium; C38H34NO4P; lithium bromide; zinc dibromide in tetrahydrofuran T=20°C; Inert atmosphere; 2: With hydrogenchloride; water in tetrahydrofuran; diethyl ether Inert atmosphere; optical yield given as percent eeenantioselective reaction;