potassium carbonate in water T=170°C; 2 h;

1: chloride derivative / 0 °C / |Reflux 2: tris(dibenzylideneacetone)dipalladium(0) chloroform complex; 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl; caesium carbonate / 20 - 130 °C 3: lithium hydroxide hydrate; water / methanol; tetrahydrofuran / |Reflux View Scheme

1: tris(dibenzylideneacetone)dipalladium(0) chloroform complex; 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl; caesium carbonate / 20 - 130 °C 2: lithium hydroxide hydrate; water / methanol; tetrahydrofuran / |Reflux View Scheme

T=140°C;