1,3,5-三甲氧基苯合成路线 （共 273 条）
反应条件
dihydrogen peroxide; sodium bromide; ethyl orthosilicate; gamma-aminopropyltriethoxysilane in 1,4-dioxane; phosphate buffer 24 h;
参考文献
Bennett, Stephanie M.; Tang, Ying; McMaster, Danielle; Bright, Frank V.; Detty, Michael R.
Journal of Organic Chemistry, 2008 , vol. 73, # 17 p. 6849 - 6852
反应条件
perchloric acid; dihydrogen peroxide; potassium bromide; NH4VO3 in methanol; water 24 h; Ambient temperature;
参考文献
Journal of the Chemical Society, Chemical Communications, , # 6 p. 611 - 612
参考文献
Will
Chemische Berichte, 1888 , vol. 21, p. 615
反应条件
pyridine; aluminium trichloride; tetreamethyl ammonium hydroxide 1.) diethyl ether, RT, 8 h, 2.) reflux, 36 h; Yield given. Multistep reaction;
参考文献
Lin; Liou; Ko; Teng
Journal of Pharmaceutical Sciences, 1992 , vol. 81, # 11 p. 1109 - 1112
反应条件
hydrogenchloride; diethyl ether und Kochen des Reaktionsprodukts mit Wasser;
参考文献
Freudenberg; Fikentscher; Harder
Justus Liebigs Annalen der Chemie, 1925 , vol. 441, p. 159,166
反应条件
n-butyllithium; N,N,N',N,-tetramethylethylenediamine 1.) ethyl ether, room temp., 26 h 2.) 0 deg C; Yield given. Multistep reaction;
参考文献
Cabiddu, Salvatore; Contini, Liliana; Fattuoni, Claudia; Floris, Costantino; Gelli, Gioanna
Tetrahedron, 1991 , vol. 47, # 44 p. 9279 - 9288
反应条件
n-butyllithium; N,N,N',N,-tetramethylethylenediamine 1.) hexanes or diethyl ether, room temp., 71 resp. 11 h 2.) 0 deg C; Multistep reaction;
参考文献
Crowther, G. P.; Sundberg, Richard J.; Sarpeshkar, Ashok M.
Journal of Organic Chemistry, 1984 , vol. 49, # 24 p. 4657 - 4663
反应条件
1: AlCl3 / 1,2-dichloro-ethane 2: 68 percent / AlCl3 / CHCl3 3: 46 percent / morpholine 4: 86 percent / BBr3 / CH2Cl2 View Scheme
参考文献
Miller, Chris P.; Collini, Michael D.; Harris, Heather A.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 14 p. 2399 - 2403
反应条件
perchloric acid in acetonitrile T=22°C; KineticsProduct distribution;
参考文献
Chiapperino, Dominic; McIlroy, Sean; Falvey, Daniel E.
Journal of the American Chemical Society, 2002 , vol. 124, # 14 p. 3567 - 3577
反应条件
1: 96 percent / AlCl3 / CH2Cl2 / 12 h / 0 - 20 °C 2: 92 percent / boron tribromide / CH2Cl2 / -78 - 20 °C View Scheme
参考文献
Thevenin, Marion; Mouray, Elisabeth; Grellier, Philippe; Dubois, Joelle
European Journal of Organic Chemistry, 2014 , vol. 2014, # 14 p. 2986 - 2992
