1,3,5-三甲氧基苯合成路线 （共 273 条）
反应条件
in water; acetone; tert-butyl alcohol Irradiation;
参考文献
Den Heijer,J. et al.
Tetrahedron, 1977 , vol. 33, p. 779 - 786
反应条件
hydrogenchloride in acetic acid 1.) 25 deg C, 1 h; 2.) 95-100 deg C, 3 h;
参考文献
Tetrahedron, , vol. 44, # 7 p. 2081 - 2086
反应条件
1: 80 percent / HCl / acetic acid / 1.) 25 deg C, 1 h; 2.) 95-100 deg C, 3 h 2: 70 percent / 1.) boron trifluoride etherate, sodium borohydride; 2.) conc. HCl, 30 percent hydrogen peroxide / tetrahydrofuran; H2O / 1.) 50 deg C, 1 h, up to 0 deg C; 2.) 50 deg C, 2 h View Scheme
参考文献
Tetrahedron, , vol. 44, # 7 p. 2081 - 2086
反应条件
dihydrogen peroxide; iodine; 1-[4-N,N-bis(carboxylatomethyl)aminophenyltelluro]-3-phenoxypropane disodium salt in diethyl ether; water
T=20°C; pH=6; 5 h;
参考文献
Higgs; Nelen; Detty
Organic letters, 2001 , vol. 3, # 3 p. 349 - 352
反应条件
N,N,N-trimethylbenzenemethanaminium dichloroiodate; zinc(II) chloride in acetic acid
0.166667 h; Ambient temperature;
参考文献
Kajigaeshi, Shoji; Kakinami, Takaaki; Moriwaki, Masayuki; Watanabe, Masakazu; Fujisaki, Shizuo; Okamoto, Tsuyoshi
Chemistry Letters, 1988 , # 5 p. 795 - 798
反应条件
iodine; 1-(p-methylbenzenesulfonyloxy)-1,2-benziodoxol-3(1H)-one in acetonitrile
18 h; Ambient temperature;
参考文献
Muraki, Takahito; Togo, Hideo; Yokoyama, Masataka
Synlett, 1998 , # 3 p. 286 - 288
反应条件
sodium periodate; sulfuric acid; dihydrogen peroxide in ethanol; water
T=50°C; 0.5 h;
参考文献
Sathiyapriya
Asian Journal of Chemistry, 2011 , vol. 23, # 1 p. 41 - 43
反应条件
dihydrogen peroxide; iodine; 1-[4-N,N-bis(carboxylatomethyl)aminophenyltelluro]-3-phenoxypropane disodium salt in diethyl ether; water
T=20°C; pH=6; 5 h;
参考文献
Higgs; Nelen; Detty
Organic letters, 2001 , vol. 3, # 3 p. 349 - 352
反应条件
1: phloroglucinol trimethyl ether With n-butyllithium in tetrahydrofuran; hexane
T=-78°C; 0.5 h;
2: N,N-dimethyl-formamide in tetrahydrofuran; hexane
T=-78 - 20°C; 2 h;
3: methanol Further stages;
参考文献
Ushijima, Sousuke; Moriyama, Katsuhiko; Togo, Hideo
Tetrahedron, 2012 , vol. 68, # 24 p. 4701 - 4709
反应条件
1: 13.0 g / iodine, silver trifluoroacetate / CHCl3 / 0.67 h
2: copper bronze
3: 4.85 g / phosphoryl chloride / 2.75 h / Heating
4: 9.6 g / boron trichloride / CH2Cl2 / 1 h / -10 °C
5: 8.25 g / zinc amalgam, conc. hydrochloric acid / acetic acid; H2O / 2 h / Heating
6: 1.) hydrobromic acid, 2.) potassium carbonate / 1.) glacial acetic acid, reflux, 18 h, 2.) DMF, 24 h
View Scheme
参考文献
Sargent, Melvyn V.; Stransky, Peter O.; Patrick, Vincent A.; White, Allan H.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 2 p. 231 - 239
