1,3,5-三甲氧基苯合成路线 （共 273 条）
反应条件
thionyl chloride; diethylamine in chloroform
T=0°C; 1 h;
参考文献
Bell, Kevin H.
Australian Journal of Chemistry, 1985 , vol. 38, # 8 p. 1209 - 1221
反应条件
in dichloromethane
T=-90 - 20°C; Kinetics; TemperatureReagent/catalyst;
参考文献
Cong, Zhiqi; Kurahashi, Takuya; Fujii, Hiroshi
Journal of the American Chemical Society, 2012 , vol. 134, # 10 p. 4469 - 4472
反应条件
acetonitrile; boron trifluoride diethyl etherate in tetrachloromethane
T=0 - 5°C;
参考文献
Ibata, Toshikazu; Yamamoto, Masahiko
Chemistry Letters, 1981 , p. 161 - 164
反应条件
boron trifluoride diethyl etherate in tetrachloromethane
T=0 - 5°C;
参考文献
Ibata, Toshikazu; Yamamoto, Masahiko
Chemistry Letters, 1981 , p. 161 - 164
反应条件
hydrogenchloride; tin(IV) chloride in water; benzene
参考文献
Laboratoire L. Lafon
Patent: US5250543 A1, 1993 ;
反应条件
1: 36.9 g / phosphoryl chloride / 1.5 h / Ambient temperature
2: 21.3 g / zinc amalgam, hydrochloric acid / acetic acid; H2O / 2 h / Heating
3: 18.0 g / phosphoryl chloride / 1.5 h / Ambient temperature
View Scheme
参考文献
Sargent, Melvyn V.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 403 - 411
反应条件
aluminium trichloride; diethyl ether
参考文献
Mukerjee et al.
Proceedings - Indian Academy of Sciences, Section A, 1952 , vol. 35, p. 82,85
反应条件
n-butyllithium
1.) hexane, 42 deg C, 2.) hexane, 42 deg C; Yield given. Multistep reaction;
参考文献
Wada, Masanori; Higashizaki, Shogo; Tsuboi, Aki
Journal of Chemical Research, Miniprint, 1985 , # 2 p. 467 - 490
反应条件
n-butyllithium
1) THF, 2) -78 deg C (sequence repeated); Yield given. Multistep reaction;
参考文献
Doorn, Johannes A. van; Frijns, John H. G.; Meijboom, Nico
Recueil des Travaux Chimiques des Pays-Bas, 1991 , vol. 110, # 11 p. 441 - 449
反应条件
1: 65 percent / AcOH; HCl / 3 h / 95 - 100 °C
2: 96 percent / H2; AcOH / Pd-C / H2O / 24 h / 20 °C / 1551.44 - 2068.59 Torr
View Scheme
参考文献
Liu, Xiaoling; Go, Mei-Lin
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 1 p. 153 - 163
