N-(3-羟基苯基)乙酰胺合成路线 （共 86 条）
反应条件
potassium carbonate; potassium iodide in acetone
Reflux;
参考文献
El Ella; Saleh; Hassan; Hamdy; El-Araby; Abouzid
Arzneimittel-Forschung/Drug Research, 2012 , vol. 62, # 8 p. 360 - 366
反应条件
1: methanol. sodium methylate; copper
2: sulfuric acid
3: aqueous hydrochloric acid
View Scheme
参考文献
Julia; Tchernoff
Bulletin de la Societe Chimique de France, 1952 , p. 546,547
反应条件
1: potassium hydroxide / tetrahydrofuran / 20 °C
2: 1,1'-bis(diphenylphosphanyl)ferrocenenickel(II) chloride; potassium phosphate / toluene / 24 h / 110 °C / |Schlenk technique
View Scheme
参考文献
Li, Xiao-Jian; Zhang, Jin-Ling; Geng, Yu; Jin, Zhong
Journal of Organic Chemistry, 2013 , vol. 78, # 10 p. 5078 - 5084
参考文献
Phillips
Journal of the Chemical Society, 1930 , p. 1910,1913
反应条件
1: potassium carbonate; potassium iodide / acetone / |Reflux
2: sodium hydroxide; water / ethanol / 7 h / |Reflux
View Scheme
参考文献
El Ella; Saleh; Hassan; Hamdy; El-Araby; Abouzid
Arzneimittel-Forschung/Drug Research, 2012 , vol. 62, # 8 p. 360 - 366
反应条件
1: glacial acetic acid; chlorine / 15 - 20 °C
2: KOH-solution
View Scheme
参考文献
Jacobs; Heidelberger; Rolf
Journal of the American Chemical Society, 1919 , vol. 41, p. 460
反应条件
sulfuric acid
T=20°C; 6 h;
参考文献
Leaym, Xiaoxuan; Kraft, Stefan; Bossmann, Stefan H.
Synthesis, 2008 , # 6 p. 932 - 942
反应条件
potassium carbonate in acetonitrile
T=70°C;
参考文献
Zhou, Feng; Han, Xiuling; Lu, Xiyan
Tetrahedron Letters, 2011 , vol. 52, # 36 p. 4681 - 4685
反应条件
potassium carbonate in acetone
8 h; Heating;
参考文献
Griera; Armengol; Reyes; Alvarez; Palomer; Cabre; Pascual; Garcia; Mauleon
European Journal of Medicinal Chemistry, 1997 , vol. 32, # 7-8 p. 547 - 570
反应条件
potassium carbonate; potassium iodide in acetone
Reflux;
参考文献
El Ella; Saleh; Hassan; Hamdy; El-Araby; Abouzid
Arzneimittel-Forschung/Drug Research, 2012 , vol. 62, # 8 p. 360 - 366
