3-羟基-4-甲氧基苯甲醛合成路线 （共 405 条）
参考文献
MERCK PATENT GMBH
Patent: WO2003/104205 A1, 2003 ;
Location in patent: Page 24 ;
参考文献
Manske
Canadian Journal of Research, Section B: Chemical Sciences, 1937 , vol. 15, p. 164
Canadian Journal of Research, Section B: Chemical Sciences, 1940 , vol. 18, p. 80,83
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Barger et al.
Chemische Berichte, 1933 , vol. 66, p. 450,459
参考文献
Schorygin; Isaguljanz; Below
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1930 , vol. 62, p. 2039,2043
Chemische Berichte, 1931 , vol. 64, p. 274,279 Anm. 12
反应条件
1: potassium fluoride; dimethylammonium chloride / toluene / 3 h / Reflux 2: sodium tetrahydroborate; silica gel / chloroform; isopropyl alcohol / 0.5 h / 20 °C View Scheme
参考文献
Mur Blanch, Nuria; Chabot, Guy G.; Quentin, Lionel; Scherman, Daniel; Bourg, Stephane; Dauzonne, Daniel
European Journal of Medicinal Chemistry, 2012 , vol. 54, p. 22 - 32
反应条件
potassium carbonate in N-methyl-acetamide
参考文献
Nikken Chemicals Co., Ltd.
Patent: US6265402 B1, 2001 ;
反应条件
potassium carbonate in N,N-dimethyl-formamide T=110°C;
参考文献
Zhang, Mei; Yang, Xiao-Ying; Tang, Wei; Groeneveld, Tom W. L.; He, Pei-Lan; Zhu, Feng-Hua; Li, Jia; Lu, Wei; Blom, Anna M.; Zuo, Jian-Ping; Nan, Fa-Jun
ACS Medicinal Chemistry Letters, 2012 , vol. 3, # 4 p. 317 - 321
参考文献
American Home Products Corporation
Patent: US5124455 A1, 1992 ;
反应条件
ammonium acetate 5 h; Reflux;
参考文献
Reis, Joana; Oliveira, Catarina; Milhazes, Nuno; Vina, Dolores; Borges, Fernanda
Letters in Drug Design and Discovery, 2012 , vol. 9, # 10 p. 958 - 961
参考文献
Puri; Seshadri
Journal of the Chemical Society, 1955 , p. 1589,1592
反应条件
1: K2CO3 / acetone / 6 h / Heating 2: 80 percent / AcOH; ethylenediamine / 20 °C 3: 93 percent / LAH / tetrahydrofuran / 24 h / 20 °C View Scheme
参考文献
Cabedo, Nuria; Protais, Philippe; Cassels, Bruce K.; Cortes, Diego
Journal of Natural Products, 1998 , vol. 61, # 6 p. 709 - 712
