3-羟基-4-甲氧基苯甲醛合成路线 （共 405 条）
反应条件
1: 95 percent / CH2Cl2 / 22 h 2: 91 percent / HCO2NH4 / Pd/C / methanol / 3 h / Heating View Scheme
参考文献
Blase; Banerjee
Synthetic Communications, 1995 , vol. 25, # 20 p. 3187 - 3197
反应条件
hydrazine hydrate; potassium hydroxide in ethylene glycol T=130 - 190°C; Wolff-Kishner Reduction; 6 h; Inert atmosphere;
参考文献
Sacher, Joshua R.; Weinreb, Steven M.
Tetrahedron, 2011 , vol. 67, # 52 p. 10203 - 10207
参考文献
Cheng, Xue-Min; Erasga, Noe; Filzen, Gary Frederick; Geyer, Andrew; Lee, Chitase; Trivedi, Bharat Kalidas
Patent: US2003/207924 A1, 2003 ;
反应条件
ammonium acetate in butan-1-ol Heating;
参考文献
Wasserman, Harry H.; Robinson, Ralph P.; Carter, Charles G.
Journal of the American Chemical Society, 1983 , vol. 105, # 6 p. 1697 - 1698
反应条件
ammonium acetate; malonic acid in ethanol; water
参考文献
THE NUTRASWEET COMPANY, (a Delaware corporation)
Patent: EP355819 A1, 1990 ;
反应条件
1: 81 percent / K2CO3, KI / dimethylformamide / 21 h / 65 °C 2: 92 percent / sulfamic acid, aq. AcOH, aq. NaClO2 / 1 h / Ambient temperature 3: 98 percent / SOCl2 / toluene; dimethylformamide / 5 h / Heating 4: 1.) NaH / 1.) THF, 0.25 h, 2.) THF, RT, 0.5 h View Scheme
参考文献
Cook, David C.; Jones, Ronald H.; Kabir, Humayun; Lythgoe, David J.; McFarlane, Ian M.; Pemberton, Clive; Thatcher, Alan A.; Thompson, David M.; Walton, John B.
Organic Process Research and Development, 1998 , vol. 2, # 3 p. 157 - 168
反应条件
1.1: potassium tert-butylate / tetrahydrofuran / 0.5 h / 25 °C 1.2: 12 h / 25 °C 2.1: triethanolamine; palladium diacetate / 4 h / 100 °C View Scheme
参考文献
Csuk, Rene; Albert, Sabrina
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2011 , vol. 66, # 3 p. 311 - 316
反应条件
1-butylpyridinium bromide 0.05 h; microwave irradiation;
参考文献
Chauhan, Shive M. S.; Jain, Nidhi
Journal of Chemical Research, 2004 , # 10 p. 693 - 694
反应条件
1: 48 percent / NaH / tetrahydrofuran; dimethylsulfoxide / 20 h / Ambient temperature 2: 100 percent / H2 / Pd/C 3: 67 percent / polyphosphoric acid / CHCl3 / 40 °C View Scheme
参考文献
Beugelmans, Rene; Chastanet, Jacqueline; Ginsburg, Helene; Quintero-Cortes, Leticia; Roussi, Georges
Journal of Organic Chemistry, 1985 , vol. 50, # 24 p. 4933 - 4938
反应条件
pyridine; iodine cloride in 1,4-dioxane T=0 - 20°C; 144 h; Inert atmosphereDarkness;
参考文献
Fischer, Joshua; Savage, G. Paul; Coster, Mark J.
Organic Letters, 2011 , vol. 13, # 13 p. 3376 - 3379
