(4-氯苯基)-(1H-吡咯-3-基)甲酮合成路线 （共 5 条）
反应条件
trifluoroacetic acid T=72°C; 36 h; equilibrium;
参考文献
Carson, John R.; Davis, Nancy M.
Journal of Organic Chemistry, 1981 , vol. 46, # 5 p. 839 - 843
反应条件
sodium hydroxide in 1,4-dioxane
15 h; Ambient temperature;
参考文献
Papireddy, Kancharla; Smilkstein, Martin; Kelly, Jane Xu; Shweta; Salem, Shaimaa M.; Alhamadsheh, Mamoun; Haynes, Stuart W.; Challis, Gregory L.; Reynolds, Kevin A.
Journal of Medicinal Chemistry, 2011 , vol. 54, # 15 p. 5296 - 5306
反应条件
trifluorormethanesulfonic acid
T=72°C; 24 h; equilibrium;
参考文献
Carson, John R.; Davis, Nancy M.
Journal of Organic Chemistry, 1981 , vol. 46, # 5 p. 839 - 843
反应条件
1: AlCl3 / CH2Cl2 / 1.5 h / Ambient temperature
2: 5N aq. AlCl3 / dioxane / Ambient temperature
View Scheme
参考文献
Nicolaou, Ioannis; Demopoulos, Vassilis J.
Journal of Heterocyclic Chemistry, 1998 , vol. 35, # 6 p. 1345 - 1348
反应条件
in 1,4-dioxane
24 h; Ambient temperature;
参考文献
Cadamuro, Silvano; Degani, Iacopo; Dughera, Stefano; Fochi, Rita; Gatti, Antonella; Piscopo, Laura
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 2 p. 273 - 284
