(S)-N-BOC-4-溴苯丙氨酸合成路线 （共 12 条）
反应条件
2: trifluoroacetic acid / dichloromethane / 2 h / 25 °C
3: sodium hydrogencarbonate / water; 1,4-dioxane / 3 h / 25 °C
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参考文献
Prior, Allan M.; Kim, Yunjeong; Weerasekara, Sahani; Moroze, Meghan; Alliston, Kevin R.; Uy, Roxanne Adeline Z.; Groutas, William C.; Chang, Kyeong-Ok; Hua, Duy H.
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 23 p. 6317 - 6320
反应条件
1: potassium carbonate / N,N-dimethyl-formamide / 4 h / 20 °C
2: ammonia; methanol / 0.25 h / -50 - 20 °C
3: triethylamine; trifluoroacetic anhydride / dichloromethane / 3.5 h / 0 - 20 °C / Inert atmosphere
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参考文献
PROZYMEX A/S; PEDERSEN, John; LAURITZEN, Conni
Patent: WO2012/119941 A1, 2012 ;
WO 2012/119941 A1
