N-(苄氧羰基)-1,4-丁二胺合成路线 （共 19 条）
反应条件
potassium fluoride in acetonitrile 2 h; Heating;
参考文献
Samejima; Takeda; Kawase; Okada; Kyogoku
Chemical and pharmaceutical bulletin, 1984 , vol. 32, # 9 p. 3428 - 3435
反应条件
in dichloromethane
T=0 - 20°C; 25 h;
参考文献
Squire, Jennifer S.; Sutti, Alessandra; Durand, Gregory; Conlan, Xavier A.; Henderson, Luke C.
New Journal of Chemistry, 2013 , vol. 37, # 7 p. 1895 - 1905
反应条件
hydrazine hydrate in ethanol
T=0 - 20°C; 0.75 h;
参考文献
Lakanen; Coward; Pegg
Journal of Medicinal Chemistry, 1992 , vol. 35, # 4 p. 724 - 734
反应条件
trifluoroacetic acid in dichloromethane
T=0°C; 1 h;
参考文献
Luten; van Steenbergen; Lok; de Graaff; van Nostrum; Talsma; Hennink
European Journal of Pharmaceutical Sciences, 2008 , vol. 33, # 3 p. 241 - 251
反应条件
sodium hydroxide in water; N,N-dimethyl-formamide
参考文献
Bristol-Myers Squibb Company
Patent: US5583146 A1, 1996 ;
US 5583146 A
反应条件
sodium hydrogencarbonate in water; acetonitrile
参考文献
Caporale, Andrea; Woznica, Iwona; Schievano, Elisabetta; Mammi, Stefano; Peggion, Evaristo
Amino Acids, 2010 , vol. 38, # 4 p. 1269 - 1275
反应条件
sodium hydroxide; sodium chloride; potassium acetate in ethylene glycol dimethyl ether; ethanol; water; benzene
参考文献
Roussel Uclaf
Patent: US5064861 A1, 1991 ;
参考文献
CHUGAI SEIYAKU KABUSHIKI KAISHA
Patent: EP1082963 A1, 2001 ;
参考文献
Pittelkow, Michael; Lewinsky, Rasmus; Christensen, Jorn Bolstad
Synthesis, 2002 , # 15 p. 2195 - 2202
反应条件
triphenylphosphine in tetrahydrofuran; water
T=20°C; 20 h;
参考文献
Wakamiya, Tateaki; Kinoshita, Tomohiko; Hattori, Yoshihide; Yamaguchi, Yoshihiro; Naoki, Hideo; Corzo, Gerardo; Nakajimal, Terumi
Bulletin of the Chemical Society of Japan, 2004 , vol. 77, # 2 p. 331 - 340
