N-(苄氧羰基)-1,4-丁二胺合成路线 （共 19 条）
反应条件
sodium hydroxide in tetrahydrofuran
T=0°C;
参考文献
Blagbrough, Ian S.; Moya, Eduardo; Walford, Steven P.
Tetrahedron Letters, 1996 , vol. 37, # 4 p. 551 - 554
反应条件
sodium hydroxide; water; sodium acetate in ethanol
T=4°C; 20 h;
参考文献
Samejima; Takeda; Kawase; Okada; Kyogoku
Chemical and pharmaceutical bulletin, 1984 , vol. 32, # 9 p. 3428 - 3435
反应条件
sodium hydroxide; water; sodium acetate in ethanol
T=4°C; 20 h;
参考文献
Samejima; Takeda; Kawase; Okada; Kyogoku
Chemical and pharmaceutical bulletin, 1984 , vol. 32, # 9 p. 3428 - 3435
反应条件
1: 82 percent / aq. NaOH / 16 h / 0 - 20 °C
2: 76 percent / TFA / CH2Cl2 / 1 h / 0 °C
View Scheme
参考文献
Blagbrough, Ian S.; Moya, Eduardo; Walford, Steven P.
Tetrahedron Letters, 1996 , vol. 37, # 4 p. 551 - 554
反应条件
1: Et3N / toluene / 2 h / 0 °C
2: 4.24 g / NaN3; Bu4NBr / toluene; H2O / 24 h / 70 °C
3: PPh3 / tetrahydrofuran; H2O / 20 h / 20 °C
View Scheme
参考文献
Wakamiya, Tateaki; Kinoshita, Tomohiko; Hattori, Yoshihide; Yamaguchi, Yoshihiro; Naoki, Hideo; Corzo, Gerardo; Nakajimal, Terumi
Bulletin of the Chemical Society of Japan, 2004 , vol. 77, # 2 p. 331 - 340
反应条件
1: 4.24 g / NaN3; Bu4NBr / toluene; H2O / 24 h / 70 °C
2: PPh3 / tetrahydrofuran; H2O / 20 h / 20 °C
View Scheme
参考文献
Wakamiya, Tateaki; Kinoshita, Tomohiko; Hattori, Yoshihide; Yamaguchi, Yoshihiro; Naoki, Hideo; Corzo, Gerardo; Nakajimal, Terumi
Bulletin of the Chemical Society of Japan, 2004 , vol. 77, # 2 p. 331 - 340
反应条件
hydrogenchloride in acetic acid
参考文献
Lawson; Leafer Jr.; Tewes; Rao
Hoppe-Seyler's Zeitschrift fuer physiologische Chemie, 1968 , vol. 349, # 2 p. 251 - 262
反应条件
sodium hydroxide in chloroform
T=20°C; Substitution; Product distribution;
参考文献
Hara, Takeshi; Xu, Yong Ji; Sasaki, Hitomi; Niitu, Masaru; Samejima, Keijiro
Journal of Labelled Compounds and Radiopharmaceuticals, 2000 , vol. 43, # 10 p. 1005 - 1012
反应条件
2: BH3 / tetrahydrofuran / 18 h / Heating
View Scheme
参考文献
Golding, Bernard T.; O"Sullivan, Mary C.; Smith, Lewis L.
Tetrahedron Letters, 1988 , vol. 29, # 50 p. 6651 - 6654
