4-(2,2,2-三氟乙氧基)硝基苯合成路线 （共 13 条）
反应条件
1: 2,2,2-trifluoroethanol With sodium t-butanolate in toluene
T=0 - 20°C; 0.25 h; Inert atmosphere;
2: (4-nitrophenyl)(phenyl)iodonium triflate in toluene
T=0 - 20°C; Inert atmosphere; Reagent/catalystSolventTimeTemperature; chemoselective reaction;
参考文献
Ghosh, Raju; Lindstedt, Erik; Jalalian, Nazli; Olofsson, Berit
ChemistryOpen, 2014 , vol. 3, # 2 p. 54 - 57
反应条件
sodium hydride in N,N,N',N',N'',N''-hexamethylphosphoric triamide
1.) r.t., 2.) 110 deg C, 8 h;
参考文献
Preschera, Dietrich; Thiele, Thomas; Ruhmann, Ralf
Journal of Fluorine Chemistry, 1996 , vol. 79, # 2 p. 145 - 148
反应条件
copper(l) iodide; caesium carbonate; ethyl 2-oxo-cyclohexanecarboxylate
17 h; Neat (no solvent)Reflux;
参考文献
Vukga, Daniela; Legros, Juelien; Crousse, Benoit; Bonnet-Delpon, Daniele
European Journal of Organic Chemistry, 2009 , # 21 p. 3513 - 3518
