1: benzyl (S)-2-hydroxymethylpyrrolidine-1-carboxylate With sodium chlorite; sodium dihydrogenphosphate; 1-MeAZADO(1+)*Cl(1-) in dichloromethane; water T=25°C; 15 h; 2: With 2-methyl-but-2-ene in dichloromethane; water 3: diazomethane With hydrogenchloride; sodium hydroxide Product distribution / selectivity; more than 3 stages;
参考文献
Nissan Chemical Industries, Ltd.
Patent: US2009/124806 A1, 2009 ;
Location in patent: Page/Page column 5-7 ;
