N-(4-氧代-1,7-二氢吡咯并[2,3-d]嘧啶-2-基)乙酰胺合成路线 （共 4 条）
反应条件
pyridine
T=85°C; 0.5 h;
参考文献
Akimoto, Hiroshi; Imamiya, Eiko; Hitaka, Takenori; Nomura, Hiroaki; Nishimura, Susumu
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 1637 - 1644
反应条件
1: pyridine / 5 h / Heating
2: 0.25 N aq. NaOH / 0.5 h / Ambient temperature
View Scheme
参考文献
Benghiat, Eric; Crooks, Peter A.
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1023 - 1025
反应条件
sodium hydroxide
0.5 h; Ambient temperature; Yield given;
参考文献
Benghiat, Eric; Crooks, Peter A.
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1023 - 1025
反应条件
1: 1.) LDA / 1.) Me2SO, RT, 5 min, 2.) Me2SO, RT, 5 min
2: 64 percent / 40percent aq. MeNH2 / 1.5 h
View Scheme
参考文献
Beauchamp, Lilia M.; Dolmatch, Bart L.; Schaeffer, Howard J.; Collins, Peter; Bauer, D. J.; et al.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 8 p. 982 - 987
