反应条件
1: pyridine, Ph3PBr2 / acetonitrile / 0 °C 2: acetonitrile / 24 h / Heating 3: 56 percent / NaN(SiMe3)2 / tetrahydrofuran / 1.) room temperature, 2.) -90 deg C 4: 100 percent / H+ / tetrahydrofuran 5: 86 percent / LiAlH4 / tetrahydrofuran / -70 °C 6: 94 percent / CBr4, Ph3P / CH2Cl2 / 1.) 0 deg C, 15 min, 2.) room temperature, 1 h 7: 95 percent / acetonitrile / Heating 8: 76 percent / NaN(SiMe3)2 / tetrahydrofuran / -80 °C 9: 92 percent / LiOH / tetrahydrofuran; H2O View Scheme
参考文献
Journal of Organic Chemistry, , vol. 60, # 20 p. 6627 - 6630
