4-(2-氰基苯基)1-丁烯合成路线 （共 8 条）
反应条件
1: 2-methylbenzonitrile With N,N'-dimethyl-N,N'-propyleneurea; lithium diisopropyl amide in tetrahydrofuran; hexane T=-78°C; Metallation; 0.25 h; 2: allyl bromide in tetrahydrofuran; hexane T=-78°C; Alkylation; 0.5 h;
参考文献
Bunce, Richard A.; Johnson, Lara B.
Organic Preparations and Procedures International, 1999 , vol. 31, # 4 p. 407 - 412
反应条件
boron trifluoride diethyl etherate in dichloromethane 5 h; Heating;
参考文献
Nishiyama, Hisao; Sakuta, Koji; Osaka, Noriyuki; Arai, Hiroyuki; Matsumoto, Makoto; Itoh, Kenji
Tetrahedron, 1988 , vol. 44, # 9 p. 2413 - 2426
反应条件
boron trifluoride diethyl etherate in dichloromethane T=0°C; 0.333333 h;
参考文献
Tetrahedron, , vol. 44, # 9 p. 2413 - 2426
反应条件
2: HONH2*HCl, NaOAc / ethanol / 40 h / Ambient temperature 3: pyridine; CH2Cl2 / 1.5 h / Ambient temperature 4: 97 percent / BF3*Et2O / CH2Cl2 / 5 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 44, # 9 p. 2413 - 2426
反应条件
1: HONH2*HCl, NaOAc / ethanol / 40 h / Ambient temperature 2: pyridine; CH2Cl2 / 1.5 h / Ambient temperature 3: 97 percent / BF3*Et2O / CH2Cl2 / 5 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 44, # 9 p. 2413 - 2426
反应条件
1: pyridine; CH2Cl2 / 1.5 h / Ambient temperature 2: 97 percent / BF3*Et2O / CH2Cl2 / 5 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 44, # 9 p. 2413 - 2426
反应条件
1: 1,2-Benzenedicarbonitrile With ammonia; sodium 0.0833333 h; 2: 4-bromo-but-1-ene T=-33°C;
参考文献
Russian Journal of Organic Chemistry, , vol. 49, # 1 p. 138 - 144
Zh. Org. Khim., , vol. 49, # 1 p. 142 - 148
反应条件
potassium in ammonia T=-33°C; 3.5 h; Product distribution; Further Variations:reaction time;
参考文献
Russian Journal of Organic Chemistry, , vol. 42, # 9 p. 1280 - 1288
