1: hydrogenchloride; water / 12 h / 100 °C 2: sulfuric acid / water / 12 h / 80 °C / Inert atmosphere 3: Thermomyces lanuginosus lipase; sodium hydroxide / acetonitrile / 35 °C / pH 5.6 - 6 / aq. acetate buffer; Enzymatic reaction View Scheme
参考文献
Badland, Matthew; Burns, Michael P.; Carroll, Robert J.; Howard, Roger M.; Laity, Daniel; Wymer, Nathan J.
Green Chemistry, 2011 , vol. 13, # 10 p. 2888 - 2894
1: hydrogenchloride; water / 12 h / 100 °C
2: sulfuric acid / water / 12 h / 80 °C / Inert atmosphere
3: Thermomyces lanuginosus lipase; sodium hydroxide / acetonitrile / 35 °C / pH 5.6 - 6 / aq. acetate buffer; Enzymatic reaction
4: tetrahydrofuran; toluene / 10 °C
View Scheme
参考文献
Badland, Matthew; Burns, Michael P.; Carroll, Robert J.; Howard, Roger M.; Laity, Daniel; Wymer, Nathan J.
Green Chemistry, 2011 , vol. 13, # 10 p. 2888 - 2894
1: With Br(1-)*C24H30N4Rh(1+); water in isopropyl alcohol
T=25°C; 0.5 h; Inert atmosphere;
2: With potassium tert-butylate in isopropyl alcohol
T=25°C; 12 h; Inert atmosphere;
参考文献
Daw, Prosenjit; Sinha, Arup; Rahaman, S. M. Wahidur; Dinda, Shrabani; Bera, Jitendra K.
Organometallics, 2012 , vol. 31, # 9 p. 3790 - 3797
