1-(5-氯-2-硝基苯基)-3,4-二氢-6,7-二甲氧基异喹啉合成路线 (共 5 条)
反应条件
phosphorus pentoxide; trichlorophosphate in xylene
3 h; Heating;
参考文献
Nyerges, Miklos; Viranyi, Andrea; Zhang, Weimin; Groundwater, Paul W.; Blasko, Gabor; Toke, Laszlo
Tetrahedron, 2004 , vol. 60, # 44 p. 9937 - 9944
反应条件
1: thionyl chloride / benzene / 12 h / 70 - 75 °C
2: pyridine / benzene / 20 °C
3: POCl3 / acetonitrile / Heating
View Scheme
参考文献
Kuo, Chen-Yuan; Wu, Ming-Jung; Kuo, Yao-Haur
European Journal of Medicinal Chemistry, 2006 , vol. 41, # 8 p. 940 - 949
反应条件
1: pyridine / benzene / 20 °C
2: POCl3 / acetonitrile / Heating
View Scheme
参考文献
Kuo, Chen-Yuan; Wu, Ming-Jung
Journal of the Chinese Chemical Society, 2005 , vol. 52, # 5 p. 965 - 974
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Kuo, Chen-Yuan; Wu, Ming-Jung; Kuo, Yao-Haur
European Journal of Medicinal Chemistry, 2006 , vol. 41, # 8 p. 940 - 949
反应条件
tin(ll) chloride in ethyl acetate
T=80°C; 30 h;
参考文献
Kuo, Chen-Yuan; Wu, Ming-Jung
Journal of the Chinese Chemical Society, 2005 , vol. 52, # 5 p. 965 - 974
反应条件
tin(ll) chloride in ethyl acetate
30 h; Heating;
参考文献
Kuo, Chen-Yuan; Wu, Ming-Jung; Kuo, Yao-Haur
European Journal of Medicinal Chemistry, 2006 , vol. 41, # 8 p. 940 - 949