苯并呋喃并[3,2-d]嘧啶-2,4(1H,3H)-二酮合成路线 （共 6 条）
反应条件
1: With sodium hydroxide in ethanol
1 h; Reflux;
2: With hydrogenchloride in ethanol; water
T=20°C;
参考文献
UNIVERSITY OF BASEL; CMILJANOVIC, Vladimir; CMILJANOVIC, Natasa; GIESE, Bernd; WYMANN, Matthias
Patent: WO2010/52569 A2, 2010 ;
Location in patent: Page/Page column 242 ;
WO 2010/052569 A2
反应条件
in toluene
T=115°C; Inert atmosphereReflux;
参考文献
UNIVERSITY OF BASEL; CMILJANOVIC, Vladimir; CMILJANOVIC, Natasa; GIESE, Bernd; WYMANN, Matthias
Patent: WO2010/52569 A2, 2010 ;
Location in patent: Page/Page column 240-241 ;
WO 2010/052569 A2
反应条件
acetic acid; sodium nitrite
T=45 - 50°C;
参考文献
Patil, V. M.; Sangapure, S. S.; Agasimundin, Y. S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 2 p. 132 - 135
反应条件
1: 75 percent / hydrazine hydrate / ethanol / 4 h / Heating
2: 80 percent / NaNO2, 50percent aq. acetic acid / 45 - 50 °C
View Scheme
参考文献
Patil, V. M.; Sangapure, S. S.; Agasimundin, Y. S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 2 p. 132 - 135
参考文献
Sangapure,S.S.; Agasimundin,Y.S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1976 , vol. 14, p. 688 - 691
参考文献
Sangapure,S.S.; Agasimundin,Y.S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1976 , vol. 14, p. 688 - 691
