5-溴噻吩-2-羧酸叔丁酯合成路线

参考文献

Frizler, Maxim; Schmitz, Janina; Schulz-Fincke, Anna-Christina; Guetschow, Michael
Journal of Medicinal Chemistry, 2012 , vol. 55, # 12 p. 5982 - 5986

7311-63-95-溴-2-羧基噻吩+

75-65-0叔丁醇

62224-20-85-溴噻吩-2-羧酸叔丁酯

参考文献

Wright, Stephen W.; Hageman, David L.; Wright, Ann S.; McClure, Lester D.
Tetrahedron Letters, 1997 , vol. 38, # 42 p. 7345 - 7348

7311-63-95-溴-2-羧基噻吩

62224-20-85-溴噻吩-2-羧酸叔丁酯

参考文献

Pfizer Inc.
Patent: US6344485 B1, 2002 ;

3141-27-32,5-二溴噻吩+

24424-99-5二碳酸二叔丁酯

62224-20-85-溴噻吩-2-羧酸叔丁酯

参考文献

Arredondo, Juan D.; Li, Hongmei; Balsells, Jaume
Organic Syntheses, 2012 , vol. 89, p. 460 - 470

4701-17-15-溴噻吩-2-甲醛

62224-20-85-溴噻吩-2-羧酸叔丁酯

参考文献

Choong, Ingrid C.; Lew, Willard; Lee, Dennis; Pham, Phuongly; Burdett, Matthew T.; Lam, Joni W.; Wiesmann, Christian; Luong, Tinh N.; Fahr, Bruce; DeLano, Warren L.; McDowell, Robert S.; Allen, Darin A.; Erlanson, Daniel A.; Gordon, Eric M.; O'Brien, Tom
Journal of Medicinal Chemistry, 2002 , vol. 45, # 23 p. 5005 - 5022

31555-60-95-溴噻吩-2-羰酰氯+

75-65-0叔丁醇

62224-20-85-溴噻吩-2-羧酸叔丁酯

参考文献

Frizler, Maxim; Schmitz, Janina; Schulz-Fincke, Anna-Christina; Guetschow, Michael
Journal of Medicinal Chemistry, 2012 , vol. 55, # 12 p. 5982 - 5986

62224-20-85-溴噻吩-2-羧酸叔丁酯+

5419-55-6硼酸三异丙酯

925921-29-55-叔丁氧基羰基噻吩-2-硼酸

参考文献

SMITHKLINE BEECHAM CORPORATION
Patent: WO2007/18941 A2, 2007 ;
Location in patent: Page/Page column 116-117 ;
WO 2007/018941 A2