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乙二醇
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63148-62-9
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丁酮
二甲基亚砜
碳酸氢钠
471-34-1
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乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
62248-53-7
合成路线
(共 6 条)
876486-96-3
→
反应条件
62248-53-7
反应条件
hydrogenchloride; tin(ll) chloride
参考文献
Law; Johnson
Journal of the American Chemical Society, 1930 , vol. 52, p. 3623,3625
100-00-5
对硝基氯苯
→
反应条件
62248-53-7
反应条件
1: dimethylformamide / 120 °C 2: SnCl2 / ethanol / Heating View Scheme
参考文献
Clark, Robin D.; Jahangir, Alam; Severance, Daniel; Salazar, Rick; Chang, Thomas; Chang, David; Jett, Mary Frances; Smith, Steven; Bley, Keith
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 4 p. 1053 - 1056
696-63-9
4-甲氧基苯硫酚
→
反应条件
62248-53-7
反应条件
1: NiCl2*2H2O; tetrabutylammomium bromide; potassium hydroxide / 12 h / 110 °C / Inert atmosphere 2: hydrogen bromide / 4 h / Inert atmosphere; Reflux 3: potassium carbonate; potassium iodide / acetonitrile / Inert atmosphere; Reflux 4: stannous chloride-dihydrate; ethanol / 1 h / 70 °C / Inert atmosphere View Scheme
参考文献
Li, Jie; Pei, Shuchen; Zhu, Yingxi; Wu, Jianbo; Chen, Yin; Zhang, Weiyu; Wu, Yong
Letters in Drug Design and Discovery, 2012 , vol. 9, # 4 p. 379 - 388
22865-50-5
→
反应条件
62248-53-7
反应条件
1: hydrogen bromide / 4 h / Inert atmosphere; Reflux 2: potassium carbonate; potassium iodide / acetonitrile / Inert atmosphere; Reflux 3: stannous chloride-dihydrate; ethanol / 1 h / 70 °C / Inert atmosphere View Scheme
参考文献
Li, Jie; Pei, Shuchen; Zhu, Yingxi; Wu, Jianbo; Chen, Yin; Zhang, Weiyu; Wu, Yong
Letters in Drug Design and Discovery, 2012 , vol. 9, # 4 p. 379 - 388
21101-60-0
→
反应条件
62248-53-7
反应条件
1: potassium carbonate; potassium iodide / acetonitrile / Inert atmosphere; Reflux 2: stannous chloride-dihydrate; ethanol / 1 h / 70 °C / Inert atmosphere View Scheme
参考文献
Li, Jie; Pei, Shuchen; Zhu, Yingxi; Wu, Jianbo; Chen, Yin; Zhang, Weiyu; Wu, Yong
Letters in Drug Design and Discovery, 2012 , vol. 9, # 4 p. 379 - 388
350-46-9
对氟硝基苯
→
反应条件
62248-53-7
反应条件
1: NiCl2*2H2O; tetrabutylammomium bromide; potassium hydroxide / 12 h / 110 °C / Inert atmosphere 2: hydrogen bromide / 4 h / Inert atmosphere; Reflux 3: potassium carbonate; potassium iodide / acetonitrile / Inert atmosphere; Reflux 4: stannous chloride-dihydrate; ethanol / 1 h / 70 °C / Inert atmosphere View Scheme
参考文献
Li, Jie; Pei, Shuchen; Zhu, Yingxi; Wu, Jianbo; Chen, Yin; Zhang, Weiyu; Wu, Yong
Letters in Drug Design and Discovery, 2012 , vol. 9, # 4 p. 379 - 388