1,4-二(溴甲基)苯合成路线 （共 136 条）
反应条件
thiolacetic acid; potassium carbonate in methanol T=20°C; 0.5 h;
参考文献
European Journal of Organic Chemistry, , # 3 p. 541 - 549
反应条件
NH4PF6 in chloroform; acetonitrile 5 h; Heating;
参考文献
Journal of the American Chemical Society, , vol. 116, # 11 p. 4810 - 4823
反应条件
1: acetonitrile / 5 h / Heating 2: NH4PF6 / H2O View Scheme
参考文献
Tetrahedron, , vol. 42, # 6 p. 1665 - 1677
反应条件
in acetonitrile 25 h; Reflux;
参考文献
THE STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND STATE UNIVERSITY; STRONGIN, Robert, M.; SIBRIAN-VAZQUEZ, Martha
Patent: WO2011/82354 A2, 2011 ;
Location in patent: Page/Page column 30 ;
反应条件
in acetonitrile 24 h; RefluxInert atmosphere;
参考文献
Zhao, Hong-Xia; Guo, Dong-Sheng; Liu, Yu
Journal of Physical Chemistry B, 2013 , vol. 117, # 6 p. 1978 - 1987
反应条件
T=120°C; Michaelis-Arbuzov reaction; 12 h; Inert atmosphere;
参考文献
Winter, Andreas; Friebe, Christian; Hager, Martin D.; Schubert, Ulrich S.
European Journal of Organic Chemistry, 2009 , # 6 p. 801 - 809
反应条件
1: 53 percent / acetonitrile / 24 h / 20 °C 2: 70 percent / aq. NaOH / 12 h / Heating View Scheme
参考文献
Yang, Wen; Giandomenico, Christen M.; Sartori, Michael; Moore, Dennis A.
Tetrahedron Letters, 2003 , vol. 44, # 12 p. 2481 - 2483
反应条件
Yield given. Multistep reaction;
参考文献
Yaouanc, Jean-Jacques; Bris, Nathalie Le; Gall, Guenaelle Le; Clement, Jean-Claude; Handel, Henri; Abbayes, Herve des
Journal of the Chemical Society, Chemical Communications, 1991 , # 4 p. 206 - 207
反应条件
1: lead nitrate; water 2: HCl 3: acetic acid anhydride / 160 °C / man erwaermt das Produkt mit Sodaloesung und faellt die Loesung mit Schwefelsaeure 4: NaOH-solution View Scheme
参考文献
Loew
Justus Liebigs Annalen der Chemie, 1885 , vol. 231, p. 363
参考文献
Wang, Jianjun; Yang, Chang-Tong; Kim, Young-Seung; Sreerama, Subramanya G.; Cao, Qizhen; Li, Zi-Bo; He, Zhengjie; Chen, Xiaoyuan; Liu, Shuang
Journal of Medicinal Chemistry, 2007 , vol. 50, # 21 p. 5057 - 5069
