1: N-bromosuccinimide 2: benzene / 1.) 20 deg C, 2 h, 2.) 60-70 deg C, 4 h 3: NaOH / diethyl ether / 4 h 4: H2SO4 / aq. ethanol / 2 h 5: 94 percent / CaCl2 / 72 h / Ambient temperature View Scheme
参考文献
Landor, Stephen R.; Landor, Phyllis, D.; Kalli, Michael
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 12 p. 2921 - 2926
sodium carbonate; palladium diacetate; N-(α-methylbenzylidene)isopropylamine in various solvent(s) T=140°C; 39 h; Yield givenYields of byproduct given. Title compound not separated from byproducts;
参考文献
Ohff, Manuela; Ohff, Andreas; Milstein, David
Chemical Communications, 1999 , # 4 p. 357 - 358
1: (4-Methylphenyl)-magnesium bromide With copper(l) iodide in diethyl ether T=0°C; 1 h; 2: 3-methyl-acrylic acid,methyl ester in diethyl ether Michael addition; 3 h; Further stages.;
参考文献
Loh; Hu
Organic letters, 2001 , vol. 3, # 2 p. 279 - 281
Katritzky, Alan R.; Baker, Victor J.; Brito-Palma, Fernando M. S.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1980 , p. 1739 - 1745
