1: With bromine in n-heptane T=20°C; 1 h; Inert atmosphere; 2: With potassium carbonate in n-heptane; acetonitrile T=60°C; 2 h; Inert atmosphere; optical yield given as percent de;
参考文献
Organic Process Research and Development, , vol. 16, # 2 p. 262 - 268
Jaxa-Chamiec, Albert A.; Sammes, Peter G.; Kennewell, Peter D.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 170 - 175
in tetrahydrofuran a cold (-78°C) soln. of trimethylstannyl-lithium in dry THF was allowed to react with methyl (E)-2-butenoate for 5 min; the mixt. was stirred under dry Ar atm. at -78°C for 15 min;; column chromy. (in mixt. of methanol and diethyl ether) followed by the elution with diethyl ether; removal of the solvent by distn.;
参考文献
Piers, Edward; Morton, Howard E.; Chong, J. Michael
Canadian Journal of Chemistry, 1987 , vol. 65, p. 78 - 87
in tetrahydrofuran a cold (-20°C) soln. of ((CH3)3SnCuSC6H5)Li in dry THF was allowed to react with methyl(E)-2-butenoate; the mixt. was stirred under dry Ar atm. at -20°C for 15 min and at room temp. for 1 h;; the slurry (MeOH/Et2O) was filtered through a short column of Florisil, then the column was eluted with diethyl ether; removal of the solvent by distn. (air-bath temp.41-50°C/0.2 Torr); elem anal.;
参考文献
Piers, Edward; Morton, Howard E.; Chong, J. Michael
Canadian Journal of Chemistry, 1987 , vol. 65, p. 78 - 87
