巯基乙酸乙酯合成路线

参考文献

Hanefeld, Wolfgang; Bercin, Erdogan
Archiv der Pharmazie (Weinheim, Germany), 1984 , vol. 317, # 1 p. 74 - 79

参考文献

Weidner, Karin; Giroult, Andre; Panchaud, Philippe; Renaud, Philippe
Journal of the American Chemical Society, 2010 , vol. 132, # 49 p. 17511 - 17515

394-47-82-氟苯腈+

623-51-8巯基乙酸乙酯

34761-09-63-氨基-苯并[b]噻吩-2-羧酸乙酯

参考文献

BAELL, Jonathan Bayldon; STREET, Ian Philip; SLEEBS, Brad Edmund
Patent: WO2012/131297 A1, 2012 ;
Location in patent: Page/Page column 85 ;
WO 2012/131297 A1

623-51-8巯基乙酸乙酯+

612-24-82-硝基苯甲腈

34761-09-63-氨基-苯并[b]噻吩-2-羧酸乙酯

参考文献

Romagnoli, Romeo; Baraldi, Pier Giovanni; Kimatrai Salvador, Maria; Preti, Delia; Aghazadeh Tabrizi, Mojgan; Bassetto, Marcella; Brancale, Andrea; Hamel, Ernest; Castagliuolo, Ignazio; Bortolozzi, Roberta; Basso, Giuseppe; Viola, Giampietro
Journal of Medicinal Chemistry, 2013 , vol. 56, # 6 p. 2606 - 2618

873-32-5邻氯苯腈+

623-51-8巯基乙酸乙酯

34761-09-63-氨基-苯并[b]噻吩-2-羧酸乙酯

参考文献

Xu, Sheng-Zhen; Hu, Yang-Gen; Ding, Ming-Wu
Synthesis, 2006 , # 24 p. 4180 - 4186

623-51-8巯基乙酸乙酯+

55557-52-32-氯-3-氰基吡嗪

56881-21-17-氨基噻吩并[2,3-B]吡嗪-6-羧酸乙酯

参考文献

Kamata, Makoto; Yamashita, Tohru; Kina, Asato; Funata, Masaaki; Mizukami, Atsushi; Sasaki, Masako; Tani, Akiyoshi; Funami, Miyuki; Amano, Nobuyuki; Fukatsu, Kohji
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 11 p. 3643 - 3647

623-51-8巯基乙酸乙酯+

10191-60-3N-氰亚胺基-S,S-二硫代碳酸二甲酯

39736-29-34-氨基-2-(甲基硫代)噻唑-5-羧酸乙酯

参考文献

Yang, Beom-Seok; Kim, Yong-Zu; Park, Tae-Kyo; Woo, Sung-Ho; Lee, Hyang-Sook; Kim, Sun-Young; Cho, Jong-Un; Lee, Hong-Bum
Patent: US2013/72482 A1, 2013 ;
Location in patent: Paragraph 0315-0317 ;

39736-29-34-氨基-2-(甲基硫代)噻唑-5-羧酸乙酯

参考文献

Abbott Laboratories
Patent: US5326776 A1, 1994 ;
US 5326776 A

36404-88-32-氯-3-吡啶甲醛+

623-51-8巯基乙酸乙酯

59944-78-4噻吩并[2,3-b]吡啶-2-羧酸乙酯

参考文献

Buckman, Brad Owen; Nicholas, John Beamond; Ramphal, Johnnie Y.; Emayan, Kumaraswamy; Seiwert, Scott D.
Patent: US2014/94456 A1, 2014 ;
Location in patent: Paragraph 0543-0544 ;

6602-54-62-氯-3-氰基吡啶+

623-51-8巯基乙酸乙酯

52505-46-13-氨基噻吩并[2,3-b]吡啶-2-甲酸乙酯

参考文献

Lauria, Antonino; Abbate, Ilenia; Patella, Chiara; Martorana, Annamaria; Dattolo, Gaetano; Almerico, Anna Maria
European Journal of Medicinal Chemistry, 2013 , vol. 62, p. 416 - 424