3-二甲胺基-1,2-丙二醇合成路线 （共 16 条）
反应条件
sodium hydride in xylene T=130°C; 3 h;
参考文献
Synlett, , # 14 p. 2284 - 2286
反应条件
sodium hydride in benzene 18.5 h; Heating;
参考文献
Pharmaceutical Research, , vol. 22, # 3 p. 362 - 372
反应条件
potassium tert-butylate
反应条件
1.1: 1,1'-carbonyldiimidazole / acetonitrile / 2.5 h / 20 - 35 °C / Industry scale 1.2: 21 h / 30 °C / Industry scale 2.1: 50 °C / Sealed tube View Scheme
参考文献
MERCK PATENT GMBH; PLATSCHER, Michael Wilhelm; HEIDINGER, Alfred
Patent: WO2012/159704 A1, 2012 ;
反应条件
in dichloromethane
T=20°C; 1 h;
参考文献
Grinstaff, Mark W.; Barthelemy, Philippe; Prata, Carla; Moreau, Louis
Patent: US2006/241071 A1, 2006 ;
Location in patent: Page/Page column 54-55 ;
反应条件
1H-imidazole in chloroform
T=20°C; 16 h;
参考文献
Monahan, Sean D.; Nader, Lisa; Wolff, Jon A.; Budker, Vladimir G.; Hagstrom, James E.
Patent: US2003/235916 A1, 2003 ;
Location in patent: Page 16 ;
