4-甲氧基-L-苯丙氨酸合成路线 （共 33 条）
反应条件
sodium hydroxide in water
反应条件
NADH-H+; potassium chloride; ammonium chloride; hydrogenchloride; Bacillus sphaericus wild type phenylalanine dehydrogenase in various solvent(s) T=25°C; pH=8.0; 0.666667 h;
参考文献
Organic and Biomolecular Chemistry, , vol. 2, # 18 p. 2684 - 2691
反应条件
Wilkinson's catalyst in water; acetonitrile 2 h; Heating;
参考文献
Laguzza, Bennett C.; Ganem, Bruce
Tetrahedron Letters, 1981 , vol. 22, # 16 p. 1483 - 1486
反应条件
1: 78 percent / AcONa / acetic anhydride / 1 h / Heating 2: 98 percent / aq. HCl / 3 h / Heating 3: NH4Cl; KCl; NADH / Bacillus sphaericus wild type phenylalanine dehydrogenase; aq. HCl / various solvent(s) / 0.67 h / 25 °C / pH 8.0 View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 2, # 18 p. 2684 - 2691
反应条件
1: 98 percent / aq. HCl / 3 h / Heating 2: NH4Cl; KCl; NADH / Bacillus sphaericus wild type phenylalanine dehydrogenase; aq. HCl / various solvent(s) / 0.67 h / 25 °C / pH 8.0 View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 2, # 18 p. 2684 - 2691
反应条件
hydrogenchloride 4 h; Heating;
参考文献
Ikegami, Satoru; Hayama, Takashi; Katsuki, Tsutomu; Yamaguchi, Masaru
Tetrahedron Letters, 1986 , vol. 27, # 29 p. 3403 - 3406
反应条件
1: hydrogen / Pd black / dimethylformamide / 10 h / 0 °C 2: 66 percent / 1M HCl / 72 h / 110 °C View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 59, # 1 p. 323 - 324
反应条件
1: NH2NH2.H2O 2: hydrogen / Pd black / dimethylformamide / 10 h / 0 °C 3: 66 percent / 1M HCl / 72 h / 110 °C View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 59, # 1 p. 323 - 324
反应条件
sodium hydroxide; hydrogen sulfide; copper(II) sulfate Multistep reaction;
参考文献
Journal of the American Chemical Society, , vol. 116, # 11 p. 4729 - 4737
反应条件
hydrogenchloride in water T=95 - 100°C; 6 h; Overall yield = 85.3 percent;
参考文献
Synthetic Communications, , vol. 43, # 21 p. 2892 - 2897
