3,4-亚甲基二氧苯乙基异氰酸酯合成路线 （共 6 条）
反应条件
trimethylsilylazide in 1,3,5-trimethyl-benzene
40 h; Heating;
参考文献
Slemon, Clarke E.; Hellwig, Louise C.; Ruder, Jean-Pierre; Hoskins, Eric W.; MacLean, David B.
Canadian Journal of Chemistry, 1981 , vol. 59, p. 3055 - 3060
反应条件
alpha-chloropyridine; trifluoromethylsulfonic anhydride in dichloromethane
T=-78°C; 0.333333 h; Inert atmosphere; regioselective reaction;
参考文献
In, Jinkyung; Hwang, Soonho; Kim, Changhun; Seo, Jae Hong; Kim, Sanghee
European Journal of Organic Chemistry, 2013 , # 5 p. 965 - 971
反应条件
1: 86 percent / thionyl chloride / 1 h / Heating
2: 91 percent / trimethylsilyl azide / 1,3,5-trimethyl-benzene / 40 h / Heating
View Scheme
参考文献
Slemon, Clarke E.; Hellwig, Louise C.; Ruder, Jean-Pierre; Hoskins, Eric W.; MacLean, David B.
Canadian Journal of Chemistry, 1981 , vol. 59, p. 3055 - 3060
反应条件
in toluene
T=100°C; Cooling with ice;
参考文献
Wang, Liutang; Zhang, Bin; Ji, Jianxin; Li, Bogang; Yan, Jufang; Zhang, Weiyu; Wu, Yong; Wang, Xuechao; Hou, Hui
Synthetic Communications, 2010 , vol. 40, # 1 p. 52 - 57
反应条件
boron trifluoride diethyl etherate
参考文献
Umezawa; Hoshino; Sawaki; Mori
Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 3 p. 1003 - 1005
反应条件
1: 75 percent / diisobutylaluminium hydride / diethyl ether; hexane / -78 deg C --> 0 deg C, 4 h
2: 46 percent / phosphorus oxychloride / acetonitrile / 2 h / Heating
View Scheme
参考文献
Slemon, Clarke E.; Hellwig, Louise C.; Ruder, Jean-Pierre; Hoskins, Eric W.; MacLean, David B.
Canadian Journal of Chemistry, 1981 , vol. 59, p. 3055 - 3060
