triethylamine; Methanesulfonyl azide in acetonitrile 1 h; Ambient temperature;

1: 64 percent / <1,3-bis(diphenylphosphino)propane>nickel(II) dichloride / diethyl ether; toluene / 24 h / Heating 2: dimethyl sulfoxide, phosphorus pentoxide / CH2Cl2 / 0.5 h / 0 - 20 °C 3: 1.) lithium diisopropylamide / 1.) THF, -78 deg C, 15 min 4: 85 percent / dimethyl sulfoxide, phosphorus pentoxide / CH2Cl2 / 0.5 h / 0 - 20 °C 5: 82 percent / methanesulfonyl azide, triethylamine / acetonitrile / 1 h / Ambient temperature View Scheme

1: dimethyl sulfoxide, phosphorus pentoxide / CH2Cl2 / 0.5 h / 0 - 20 °C 2: 1.) lithium diisopropylamide / 1.) THF, -78 deg C, 15 min 3: 85 percent / dimethyl sulfoxide, phosphorus pentoxide / CH2Cl2 / 0.5 h / 0 - 20 °C 4: 82 percent / methanesulfonyl azide, triethylamine / acetonitrile / 1 h / Ambient temperature View Scheme

1: 1.) lithium diisopropylamide / 1.) THF, -78 deg C, 15 min 2: 85 percent / dimethyl sulfoxide, phosphorus pentoxide / CH2Cl2 / 0.5 h / 0 - 20 °C 3: 82 percent / methanesulfonyl azide, triethylamine / acetonitrile / 1 h / Ambient temperature View Scheme

1: 85 percent / dimethyl sulfoxide, phosphorus pentoxide / CH2Cl2 / 0.5 h / 0 - 20 °C 2: 82 percent / methanesulfonyl azide, triethylamine / acetonitrile / 1 h / Ambient temperature View Scheme