反应条件
1: 2-bromo-3-hydroxypropenal With toluene-4-sulfonic acid; isopropyl alcohol in cyclohexane
T=80°C;
2: morpholin-3-ylideneamine hydrochloride With sodium methylate in methanol; ethanol
T=20°C; 2 h;
3: With triethylamine in chloroform
2 h; Heating / reflux;