5-(4-氟苯基)-1-甲基-1H-吡唑-3-三氟甲基磺酸盐合成路线 （共 4 条）
反应条件
pyridine in pyridine
2 h;
参考文献
MERCK SHARP and DOHME LIMITED
Patent: WO2003/93252 A1, 2003 ;
Location in patent: Page/Page column 58 ;
反应条件
pyridine
T=-20 - 20°C;
参考文献
Bourrain, Sylvie; Ridgill, Mark; Collins, Ian
Synlett, 2004 , # 5 p. 795 - 798
反应条件
1: 72 percent / Ph3PO; (CF3CO)2O; Et3N / 1,2-dichloro-ethane / Heating
2: 60 percent / aq. ethanol / 7 h / 60 °C
3: 96 percent / pyridine / -20 - 20 °C
View Scheme
参考文献
Bourrain, Sylvie; Ridgill, Mark; Collins, Ian
Synlett, 2004 , # 5 p. 795 - 798
反应条件
1: 60 percent / aq. ethanol / 7 h / 60 °C
2: 96 percent / pyridine / -20 - 20 °C
View Scheme
参考文献
Bourrain, Sylvie; Ridgill, Mark; Collins, Ian
Synlett, 2004 , # 5 p. 795 - 798
