反应条件
1: 2-Chlorophenyl-dihydroxyborane; 2-propenamide With potassium phosphate; [RhCl(η2:η2-cycloocta-1,5-diene)]2; bis(η3-allyl-μ-chloropalladium(II)); 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in methanol; 1,1-dimethylpropan-1-ol
T=110°C; 16 h; Inert atmosphereSealed tube;
2: 1-(iodo)-4-methylbenzene With potassium phosphate; copper(l) iodide; (1R,2R)-(-)-trans-1,2-diaminocyclohexane in methanol; 1,1-dimethylpropan-1-ol
T=20 - 130°C; 16.17 h; Inert atmosphereSealed tubeMolecular sieve;
参考文献
Zhang, Lei; Sonaglia, Lorenzo; Stacey, Jason; Lautens, Mark
Organic Letters, 2013 , vol. 15, # 9 p. 2128 - 2131
