反应条件
1: 1.) p-CH3C6H4SO3H, 2.) LAH / 1.) C6H6
2: 86 percent / pyridinium chlorochromate, sodium acetate / CH2Cl2 / 0.75 h / 25 °C
3: 1.) sodium hydride / 1.) ether, 25 deg C, 45 min, 2.) 3 h
4: 98 percent / hydrogen / 5percent Pd-C / methanol / 12 h / 25 °C
5: 93 percent / lithium aluminum hydride / diethyl ether / 2 h / 0 °C
6: 86 percent / hydrochloric acid / diethyl ether / 3 h / 25 °C
7: 97 percent / pyridine
8: 1.) sodium iodide, 2.) DBU / 1.) DMF, 50 deg C, 3.5 h, 2.) 80 deg C, 3.5 h
9: 1.) sodium hydride, 3.) aluminum chloride, lithium aluminum hydride / 1.) ether, 25 deg C, 1 h, 2.) 10 h, 3.) 0 deg C, 1 h
View Scheme
参考文献
Dhokte, U. P.; Rao, A. S.
Synthetic Communications, 1988 , vol. 18, # 8 p. 811 - 822
