1: NAP 226-90; 1,1'-carbonyldiimidazole in acetonitrile T=0 - 20°C; 1.5 h; 2: methyl-N-ethylamine With acetic acid in acetonitrile T=0 - 20°C; 3 h; 3: With sodium hydroxide in diethyl ether; water pH=> 10; Product distribution / selectivity;
1: NAP 226-90; chloroformic acid 4-nitrophenyl ester With triethylamine in dichloromethane T=0°C; 1 h; 2: methyl-N-ethylamine in dichloromethane T=20°C; 3: With sodium hydroxide in dichloromethane; water pH=> 10; Product distribution / selectivity;
参考文献
Wang, Zhi-Xian; Horne, Stephen E.; Murthy, K.S. Keshava
Patent: US2007/207990 A1, 2007 ;
Location in patent: Page/Page column 3 ;
1: 1-chloroethyl chlorocarbonate; NAP 226-90 With triethylamine in dichloromethane T=0°C; 1 h; 2: methyl-N-ethylamine in dichloromethane T=20°C; 3: With sodium hydroxide in dichloromethane; water pH=> 10; Product distribution / selectivity;
参考文献
Wang, Zhi-Xian; Horne, Stephen E.; Murthy, K.S. Keshava
Patent: US2007/207990 A1, 2007 ;
Location in patent: Page/Page column 3 ;
