1,3-双(3-氨基苯氧基)丙烷合成路线 （共 3 条）
反应条件
NH2NH2•xH2O in methanol
T=20°C; 0.5 h;
参考文献
Northwestern University; Silverman, Richard B.; Huang, He; Jing, Qing
Patent: US2014/66635 A1, 2014 ;
Location in patent: Paragraph 0030 ;
反应条件
1: potassium carbonate / N,N-dimethyl-formamide / 6 h / 60 °C
2: NH2NH2•xH2O / methanol / 0.5 h / 20 °C
View Scheme
参考文献
Huang, He; Li, Huiying; Yang, Sun; Chreifi, Georges; Martasek, Pavel; Roman, Linda J.; Meyskens, Frank L.; Poulos, Thomas L.; Silverman, Richard B.
Journal of Medicinal Chemistry, 2014 , vol. 57, # 3 p. 686 - 700
反应条件
2: Hydrogenation
View Scheme
参考文献
Ashley et al.
Journal of the Chemical Society, 1958 , p. 3298,3308
