4,4’-(1,4-丁二氧基)二苯胺合成路线 （共 6 条）
反应条件
hydrogen; palladium on activated charcoal
参考文献
Willson, M; Perie, JJ; Malecaze, F; Opperdoes, F; Callens, M
European Journal of Medicinal Chemistry, 1992 , vol. 27, # 8 p. 799 - 808
反应条件
sodium hydroxide in ethylene glycol 2.5 h; Heatingother reagent: HCl;
参考文献
Kafka, Stanislav; Klasek, Antonin; Sedmera, Petr
Collection of Czechoslovak Chemical Communications, 1995 , vol. 60, # 9 p. 1541 - 1550
反应条件
1: dimethylformamide / 10 h / Heating 2: H2 / 5percent Pd/C / tetrahydrofuran; methanol / 2280 Torr View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 28, # 11 p. 1728 - 1740
反应条件
1: 75 percent 2: 78 percent / H2 / Pd/C View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 27, # 8 p. 799 - 808
反应条件
1: sodium ethoxide / ethanol / 4 h / Heating 2: 93 percent / NaOH / ethane-1,2-diol / 2.5 h / Heating; other reagent: HCl View Scheme
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 60, # 9 p. 1541 - 1550
反应条件
1: ethanol; zinc chloride / 160 °C 2: Raney nickel; ethanol / Hydrogenation View Scheme
参考文献
Justus Liebigs Annalen der Chemie, , vol. 574, p. 85,97
